SC Free Testosterone

In the male, testosterone is mainly synthesized in the interstitial Leydig cells of the testis, and is regulated by the interstitial cell stimulating hormone (ICSH), or luteinizing hormone (LH) of the anterior pituitary (the female equivalent of ICSH). Testosterone is responsible for the development of secondary sex characteristics, such as the accessory sex organs, the prostate, seminal vesicles and the growth of facial, pubic and axillary hair. Testosterone measurements have been very helpful in evaluating hypogonadal states. Increased testosterone levels in males can be found in complete androgen resistance (testicular feminization) .9 Common causes of decreased testosterone levels in males include: hypogonadism, orchidectomy, estrogen therapy, Klinefelter's syndrome, hypopituitarism, and hepatic cirrhosis.

 

In the female, testosterone levels are normally found to be much lower than those encountered in the healthy male. Testosterone in the female comes from three sources. It is secreted in small quantities by both the adrenal glands and the ovaries, and in healthy women 50–60% of the daily testosterone production arises from peripheral metabolism of prehormones, chiefly androstenedione. Common causes of increased serum testosterone levels in females include polycystic ovaries (Stein Leventhal syndrome), ovarian tumors, adrenal tumors and adrenal hyperplasia. Virilization in women is associated with the administration of androgens and endogenous overproduction of testosterone. There appears to be a correlation between serum testosterone levels and the degree of virilization in women, although approximately 25% of women with varying degrees of virilism have serum testosterone levels that fall within the female reference range

 

Related Products:

SNIBE  free Testosterone Reagent Pack 

  • 100T (Catalog No.: 130202011M)
  • 50T   (Catalog No.: 130602011M)

    performed on the Fully-auto chemiluminescence immunoassay (CLIA) analyzer MAGLUMI